108-02 ScienCell 重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2
ScienCell 研究實驗室(ScienCell)是一家生物技術(shù)公司,其使命是實驗和治療用細胞和細胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類和動物細胞,細胞培養(yǎng)基和試劑,培養(yǎng)基添加因子,細胞來源的RNA,cDNA和蛋白質(zhì)。ScienCell的科學家們以改善生活質(zhì)量,實現(xiàn)細胞的能力,打擊人類退化性疾病為目的研究和開發(fā)各種細胞治療策略。ScienCell總部設(shè)在美國加利福尼亞州圣地亞哥,公司成立于1999年。
北京諾博萊德作為ScienCell品牌的特約經(jīng)銷商,為客戶提供,正規(guī)進口,貨期穩(wěn)定,折扣好的服務標準。
108-02 ScienCell重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2,產(chǎn)品簡介:
產(chǎn)品品牌; ScienCell
產(chǎn)品貨號:108-02
產(chǎn)品名稱:108-02 ScienCell重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2
產(chǎn)品規(guī)格:2ug
ScienCell提供純化的、高質(zhì)量的生長因子,為您的研究助力。一些專門的信號分子,在細胞的增殖和分化中發(fā)揮核心作用。只有高純度的因子才能實現(xiàn)信號通路的高強度活化。 ScienCell提供的生長因子具有以下特性:高活性,少量的蛋白即有很強效應;高純度,污染物少,干擾小。
108-02 ScienCell重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2, 產(chǎn)品說明:
BMP(骨形態(tài)發(fā)生蛋白)屬于信號蛋白的TGF-β。BMP-2是一種有效的骨誘導細胞因子,能夠誘導骨和軟骨形成,與骨傳導載體(如膠原蛋白和合成羥基磷灰石)結(jié)合。除了其成骨活性外,BMP-2還參與器官發(fā)生,特別是心臟形態(tài)發(fā)生以及肢芽形成。BMP-2 表達可以在多種組織中發(fā)現(xiàn),包括肺、脾臟、腦、肝、前列腺卵巢和小腸。BMP-2的功能形式是一種26 kDa蛋白質(zhì),由兩個相同的114個氨基酸多肽鏈組成,由單個二硫鍵連接。每個BMP-2單體表示為前體多肽的C末端部分,其中還含有用于分泌的23個氨基酸信號序列和259個氨基酸的前肽。在該前體二聚化后,前肽(也是二硫鍵連接的同源二聚體)和成熟的BMP-2配體之間的共價鍵被弗林型蛋白酶切割。
BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta of signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 is also involved in organogenesis, particularly in cardiac morphogenesis, as well as limb bud formation. BMP-2 expression can be found in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine.The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease.
ScienCell生長添加物產(chǎn)品訂購信息:
102-01 重組人干細胞因子 rhSCF,Recombinant Human Stem Cell Factor 2ug
102-02 重組人粒細胞集落刺激因子 rhG-CSF,Recombinant Human Granulocyte Colony Stimulating Factor 2ug
102-03 重組人粒細胞巨噬細胞集落刺激因子 rhM-CSF,Recombinant Human Granulocyte Macrophage Colony Stimulating Factor 5ug
102-09 重組人巨噬細胞集落刺激因子 rhM-CSF,Recombinant Human Macrophage Colony Stimulating Factor 2ug
103-01 重組人腫瘤壞死因子-alpha rhTNF-α,Recombinant Human Tumor Necrosis Factor-alpha 10ug
103-01H 重組人腫瘤壞死因子-alpha,rhTNF--His,Recombinant Human Tumor Necrosis Factor-alpha, His 10ug
103-01v 重組人腫瘤壞死因子-alpha,Variant rhTNF-α variant,Recombinant Human Tumor Necrosis Factor-alpha Variant 10ug
103-04 重組人B細胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor 5ug
103-08 重組人制瘤素-M227a.a. rhOSM,Recombinant Human Oncostatin-M 227a.a. 2ug
103-08T 重組人制瘤素-M209a.a.,Recombinant Human Oncostatin-M209a.a 2ug
103-09 重組人血管生成抑制因子K1-3 rhAngiostatin K1-3,Recombinant Human Angiostatin K1-3 10ug
103-12 重組人血管內(nèi)皮抑制素 rhEndostatin,Recombinant Human Endostatin 20ug
104-01 重組人成纖維細胞生長因子-acidic rhaFGF,Recombinant Human Fibroblast Growth Factor-acidic 10ug
104-02 重組人成纖維細胞生長因子-basic rhbFGF,Recombinant Human Fibroblast Growth Factor-basic 10ug
104-07 重組人角質(zhì)細胞生長因子 rhKGF-1,Recombinant Human Keratinocyte Growth Factor-1 2ug
104-09 重組人成纖維細胞生長因子-9 rhFGF-9,Recombinant Human Fibroblast Growth Factor-9 5ug
104-10 重組人角質(zhì)細胞生長因子-2 rhKGF-2,Recombinant Human Keratinocyte Growth Factor-2 5ug
104-19 重組人成纖維細胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19 5ug
104-21 重組人成纖維細胞生長因子-21 rhFGF-21,Recombinant Human Fibroblast Growth Factor-21 5ug
105-01 重組人胰島素生長因子-1 rhIGF-1,Recombinant Human IGF-I 20ug
105-01B 重組人DES(1-3)胰島素生長因子-1 rhIGF-BP3,Recombinant Human DES (1-3) IGF-1 20ug
105-01B3重組人胰島素生長因子-BP3,Recombinant Human IGF-BP3 5ug
105-03 重組人longR3胰島素生長因子-1 rhLR3IGF-1,Recombinant Human Long R3 Insulin-like Growth Factor-1 20ug
105-04 重組人表皮生長因子 rhEGF,Recombinant Human Epidermal Growth Factor, 100 ug 100ug
105-05 重組人血管內(nèi)皮生長因子-165 rhVEGF165,Recombinant Human VEGF165 2ug
106-06 重組人干擾素γ rhIFN-γ,Recombinant Human Interferon-gamma 20ug
107-04 重組人神經(jīng)營養(yǎng)蛋白-4 rhNT-4,Recombinant Human Neurotrophin-4 2ug
107-08 重組人纖毛神經(jīng)營養(yǎng)因子 rhCNTF,Recombinant Human Ciliary Neurotrophic Factor 5ug
107-10 重組人神經(jīng)調(diào)節(jié)蛋白 rhBTC,Recombinant Human NRG-1 EGF-like domain 10ug
107-11 重組人ErbB3片段 rhErbB3-f,Recombinant Human ErbB3 Fragment 5ug
107-12 重組人β動物纖維 rhBTC,Recombinant Human Betacellulin 5ug
108-02 重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2 2ug
108-04 重組人骨形成蛋白-4 rhBMP-4,Recombinant Human Bone Morphogenetic Protein-4 2ug
108-07 重組人骨形成蛋白-7 rhBMP-7,Recombinant Human Bone Morphogenetic Protein-7 2ug
108-08 重組人骨保護素 rHuOPG-Fc,Recombinant Human Osteoprotegerin/Fc Chimera 10ug
108-09 重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN 5ug
301-01 重組人生長激素 rhGF,Recombinant Human Growth Hormone 20ug